Reducing endogenous insulin is linked with protection against hepatic steatosis in mice

BACKGROUND: Obesity and type 2 diabetes (T2D) are closely associated with hepatic steatosis (HS), which if untreated can advance to serious liver conditions. Since insulin promotes hepatic lipogenesis, reducing hyperinsulinemia may help in treating HS. E4orf1 is an adenovirus-derived protein that im...

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Detalles Bibliográficos
Autores principales: Akheruzzaman, Md, Hegde, Vijay, Shin, Andrew C., Dhurandhar, Nikhil V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156670/
https://www.ncbi.nlm.nih.gov/pubmed/32286259
http://dx.doi.org/10.1038/s41387-020-0114-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156670/
https://www.ncbi.nlm.nih.gov/pubmed/32286259
http://dx.doi.org/10.1038/s41387-020-0114-9

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