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Elevated protein synthesis in microglia causes autism-like synaptic and behavioral aberrations

Mutations that inactivate negative translation regulators cause autism spectrum disorders (ASD), which predominantly affect males and exhibit social interaction and communication deficits and repetitive behaviors. However, the cells that cause ASD through elevated protein synthesis resulting from th...

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Detalles Bibliográficos
Autores principales: Xu, Zhi-Xiang, Kim, Gyu Hyun, Tan, Ji-Wei, Riso, Anna E., Sun, Ye, Xu, Ethan Y., Liao, Guey-Ying, Xu, Haifei, Lee, Sang-Hoon, Do, Na-Young, Lee, Chan Hee, Clipperton-Allen, Amy E., Kwon, Soonwook, Page, Damon T., Lee, Kea Joo, Xu, Baoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156673/
https://www.ncbi.nlm.nih.gov/pubmed/32286273
http://dx.doi.org/10.1038/s41467-020-15530-3