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Elevated protein synthesis in microglia causes autism-like synaptic and behavioral aberrations
Mutations that inactivate negative translation regulators cause autism spectrum disorders (ASD), which predominantly affect males and exhibit social interaction and communication deficits and repetitive behaviors. However, the cells that cause ASD through elevated protein synthesis resulting from th...
Autores principales: | Xu, Zhi-Xiang, Kim, Gyu Hyun, Tan, Ji-Wei, Riso, Anna E., Sun, Ye, Xu, Ethan Y., Liao, Guey-Ying, Xu, Haifei, Lee, Sang-Hoon, Do, Na-Young, Lee, Chan Hee, Clipperton-Allen, Amy E., Kwon, Soonwook, Page, Damon T., Lee, Kea Joo, Xu, Baoji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156673/ https://www.ncbi.nlm.nih.gov/pubmed/32286273 http://dx.doi.org/10.1038/s41467-020-15530-3 |
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