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Minimum epistasis interpolation for sequence-function relationships
Massively parallel phenotyping assays have provided unprecedented insight into how multiple mutations combine to determine biological function. While such assays can measure phenotypes for thousands to millions of genotypes in a single experiment, in practice these measurements are not exhaustive, s...
Autores principales: | Zhou, Juannan, McCandlish, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156698/ https://www.ncbi.nlm.nih.gov/pubmed/32286265 http://dx.doi.org/10.1038/s41467-020-15512-5 |
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