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Melatonin modulates red-ox state and decreases viability of rat pancreatic stellate cells

In this work we have studied the effects of pharmacological concentrations of melatonin (1 µM–1 mM) on pancreatic stellate cells (PSC). Cell viability was analyzed by AlamarBlue test. Production of reactive oxygen species (ROS) was monitored following CM-H(2)DCFDA and MitoSOX Red-derived fluorescenc...

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Detalles Bibliográficos
Autores principales: Gonzalez, Antonio, Estaras, Matias, Martinez-Morcillo, Salome, Martinez, Remigio, García, Alfredo, Estévez, Mario, Santofimia-Castaño, Patricia, Tapia, Jose A., Moreno, Noelia, Pérez-López, Marcos, Míguez, María P., Blanco-Fernández, Gerardo, Lopez-Guerra, Diego, Fernandez-Bermejo, Miguel, Mateos, Jose M., Vara, Daniel, Roncero, Vicente, Salido, Gines M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156707/
https://www.ncbi.nlm.nih.gov/pubmed/32286500
http://dx.doi.org/10.1038/s41598-020-63433-6