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Protease Inhibition Improves Healing of The Vaginal Wall after Obstetrical Injury: Results from a Preclinical Animal Model
Vaginal delivery with obstetrical trauma is a risk factor for pelvic organ prolapse later in life. Loss of fibulin-5 (FBLN5), an elastogenesis-promoting cellular matrix protein, results in prolapse in mice. Here, we evaluated effects of pregnancy, parturition, and obstetrical injury on FBLN5 content...
Autores principales: | Hamner, Jennifer, Florian-Rodriguez, Maria, Acevedo, Jesus, Shi, Haolin, Word, R. Ann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156712/ https://www.ncbi.nlm.nih.gov/pubmed/32286390 http://dx.doi.org/10.1038/s41598-020-63031-6 |
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