C-reactive protein (CRP) recognizes uric acid crystals and recruits proteases C1 and MASP1

Gout is caused by crystallization of uric acid in the form of monosodium urate (MSU) crystals, which induce a sterile inflammatory response that is hardly distinguishable from microbe-induced inflammatory responses. It is unclear, if MSU crystals (like microbes) are recognized by specific pattern re...

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Detalles Bibliográficos
Autores principales: Alberts, Anika, Klingberg, Annika, Wessig, Anne Kathrin, Combes, Christèle, Witte, Torsten, Brand, Korbinian, Pich, Andreas, Neumann, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156728/
https://www.ncbi.nlm.nih.gov/pubmed/32286427
http://dx.doi.org/10.1038/s41598-020-63318-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156728/
https://www.ncbi.nlm.nih.gov/pubmed/32286427
http://dx.doi.org/10.1038/s41598-020-63318-8

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