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Long noncoding RNA NEAT1 suppresses hepatocyte proliferation in fulminant hepatic failure through increased recruitment of EZH2 to the LATS2 promoter region and promotion of H3K27me3 methylation

Fulminant hepatic failure (FHF) refers to the rapid development of severe acute liver injury with impaired synthetic function and encephalopathy in people with normal liver or well-compensated liver disease. This study aimed to investigate the function of long noncoding RNA (lncRNA) nuclear-enriched...

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Detalles Bibliográficos
Autores principales: Wang, Qiang, Liu, Lian, Zhang, Sheng, Ming, Yingzi, Liu, Shu, Cheng, Ke, Zhao, Yujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156754/
https://www.ncbi.nlm.nih.gov/pubmed/32157157
http://dx.doi.org/10.1038/s12276-020-0387-z