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Nuclear factor IX promotes glioblastoma development through transcriptional activation of Ezrin

Enhanced migration is pivotal for the malignant development of glioblastoma (GBM), but the underlying molecular mechanism that modulates the migration of the GBM cells remains obscure. Here we show that nuclear factor IX (NFIX) is significantly upregulated in human GBM lesions compared with normal o...

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Detalles Bibliográficos
Autores principales: Liu, Zhuohao, Ge, Ruixiang, Zhou, Jiayi, Yang, Xinzhi, Cheng, Kenneth King-yip, Tao, Jingli, Wu, Dinglan, Mao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156762/
https://www.ncbi.nlm.nih.gov/pubmed/32291386
http://dx.doi.org/10.1038/s41389-020-0223-2