Expression, mutation, and methylation of cereblon‐pathway genes at pre‐ and post‐lenalidomide treatment in multiple myeloma

Cereblon (CRBN) is a target for immunomodulatory drugs. This study investigated the prognostic value of the expression of CRBN‐pathway genes on the clinical relevance of lenalidomide (Len) treatment and evaluated the levels of CRBN‐binding proteins and mutations in these genes after Len treatment. F...

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Detalles Bibliográficos
Autores principales: Tachita, Takuto, Kinoshita, Shiori, Ri, Masaki, Aoki, Sho, Asano, Arisa, Kanamori, Takashi, Yoshida, Takashi, Totani, Haruhito, Ito, Asahi, Kusumoto, Shigeru, Komatsu, Hirokazu, Yamagata, Kazufumi, Kubo, Kohmei, Tohkin, Masahiro, Fukuda, Shinsaku, Iida, Shinsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156787/
https://www.ncbi.nlm.nih.gov/pubmed/32061138
http://dx.doi.org/10.1111/cas.14352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156787/
https://www.ncbi.nlm.nih.gov/pubmed/32061138
http://dx.doi.org/10.1111/cas.14352

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