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Expression, mutation, and methylation of cereblon‐pathway genes at pre‐ and post‐lenalidomide treatment in multiple myeloma
Cereblon (CRBN) is a target for immunomodulatory drugs. This study investigated the prognostic value of the expression of CRBN‐pathway genes on the clinical relevance of lenalidomide (Len) treatment and evaluated the levels of CRBN‐binding proteins and mutations in these genes after Len treatment. F...
Autores principales: | Tachita, Takuto, Kinoshita, Shiori, Ri, Masaki, Aoki, Sho, Asano, Arisa, Kanamori, Takashi, Yoshida, Takashi, Totani, Haruhito, Ito, Asahi, Kusumoto, Shigeru, Komatsu, Hirokazu, Yamagata, Kazufumi, Kubo, Kohmei, Tohkin, Masahiro, Fukuda, Shinsaku, Iida, Shinsuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156787/ https://www.ncbi.nlm.nih.gov/pubmed/32061138 http://dx.doi.org/10.1111/cas.14352 |
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