Upregulation of ZNF148 in SDHB‐deficient gastrointestinal stromal tumor potentiates Forkhead box M1‐mediated transcription and promotes tumor cell invasion

Succinate dehydrogenase (SDH) deficiency is associated with gastrointestinal stromal tumor (GIST) oncogenesis, but the underlying molecular mechanism remains to be further investigated. Here, we show that succinate accumulation induced by SDHB loss of function increased the expression of zinc finger...

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Detalles Bibliográficos
Autores principales: Gao, Xiaodong, Ma, Chunmin, Sun, Xiangwei, Zhao, Qin, Fang, Yong, Jiang, Yuhui, Shen, Kuntang, Shen, Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156819/
https://www.ncbi.nlm.nih.gov/pubmed/32060966
http://dx.doi.org/10.1111/cas.14348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156819/
https://www.ncbi.nlm.nih.gov/pubmed/32060966
http://dx.doi.org/10.1111/cas.14348

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