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Exosomes mediate intercellular transfer of non–autonomous tolerance to proteasome inhibitors in mixed‐lineage leukemia

Proteasome inhibitors significantly improve cancer outcomes, but their use is eventually followed by proteasome inhibitor resistance and relapse. Current understanding of proteasome inhibitor resistance is limited to cell‐autonomous mechanisms; whether non–autonomous mechanisms can be implicated in...

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Detalles Bibliográficos
Autores principales: Ge, Maolin, Qiao, Zhi, Kong, Yan, Lu, Hui, Liu, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156829/
https://www.ncbi.nlm.nih.gov/pubmed/32058648
http://dx.doi.org/10.1111/cas.14351