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Targeting DNA binding proteins for cancer therapy

Dysregulation or mutation of DNA binding proteins such as transcription factors (TFs) is associated with the onset and progression of various types of disease, including cancer. Alteration of TF activity occurs in numerous cancer tissues due to gene amplification, deletion, and point mutations, and...

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Detalles Bibliográficos
Autores principales: Shiroma, Yoshitomo, Takahashi, Ryou‐u, Yamamoto, Yuki, Tahara, Hidetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156841/
https://www.ncbi.nlm.nih.gov/pubmed/32073717
http://dx.doi.org/10.1111/cas.14355