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Newcastle disease virus RNA-induced IL-1β expression via the NLRP3/caspase-1 inflammasome

Newcastle disease virus (NDV) infection causes severe inflammation and is a highly contagious disease in poultry. Virulent NDV strains (GM) induce large quantities of interleukin-1β (IL-1β), which is the central mediator of the inflammatory reaction. Excessive expression of IL-1β exacerbates inflamm...

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Detalles Bibliográficos
Autores principales: Gao, Pei, Chen, Libin, Fan, Lei, Ren, Jinlian, Du, Haoyun, Sun, Minhua, Li, Yaling, Xie, Peng, Lin, Qiuyan, Liao, Ming, Xu, Chenggang, Ning, Zhangyong, Ding, Chan, Xiang, Bin, Ren, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156904/
https://www.ncbi.nlm.nih.gov/pubmed/32293543
http://dx.doi.org/10.1186/s13567-020-00774-0