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Tauopathy Analysis in P301S Mouse Model of Alzheimer Disease Immunized with DNA and MVA Poxvirus-Based Vaccines Expressing Human Full-Length 4R2N or 3RC Tau Proteins

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by a progressive memory loss and cognitive decline that has been associated with an accumulation in the brain of intracellular neurofibrillary tangles (NFTs) formed by hyperphosphorylated tau protein, and extracellular senile pla...

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Detalles Bibliográficos
Autores principales: García-Arriaza, Juan, Marín, María Q., Merchán-Rubira, Jesús, Mascaraque, Sara M., Medina, Miguel, Ávila, Jesús, Hernández, Félix, Esteban, Mariano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157204/
https://www.ncbi.nlm.nih.gov/pubmed/32183198
http://dx.doi.org/10.3390/vaccines8010127