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Development of Tumor Cell-Based Vaccine with IL-12 Gene Electrotransfer as Adjuvant

Tumor cell-based vaccines use tumor cells as a source of tumor-associated antigens. In our study, we aimed to develop and test a tumor vaccine composed of tumor cells killed by irradiation combined with in vivo interleukin-12 gene electrotransfer as an adjuvant. Vaccination was performed in the skin...

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Detalles Bibliográficos
Autores principales: Remic, Tinkara, Sersa, Gregor, Ursic, Katja, Cemazar, Maja, Kamensek, Urska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157224/
https://www.ncbi.nlm.nih.gov/pubmed/32121641
http://dx.doi.org/10.3390/vaccines8010111