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Modeling Human Cytomegalovirus in Humanized Mice for Vaccine Testing

Human cytomegalovirus (HCMV or HHV-5) is a globally spread pathogen with strictly human tropism that establishes a life-long persistence. After primary infection, high levels of long-term T and B cell responses are elicited, but the virus is not cleared. HCMV persists mainly in hematopoietic reservo...

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Detalles Bibliográficos
Autores principales: Koenig, Johannes, Theobald, Sebastian J., Stripecke, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157227/
https://www.ncbi.nlm.nih.gov/pubmed/32079250
http://dx.doi.org/10.3390/vaccines8010089