Intratumoral Gene Electrotransfer of Plasmid DNA Encoding shRNA against Melanoma Cell Adhesion Molecule Radiosensitizes Tumors by Antivascular Effects and Activation of an Immune Response

In this study, radiotherapy was combined with the gene electrotransfer (GET) of plasmid encoding shRNA against melanoma cell adhesion molecule (pMCAM) with dual action, which was a vascular-targeted effect mediated by the silencing of MCAM and an immunological effect mediated by the presence of plas...

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Detalles Bibliográficos
Autores principales: Kranjc Brezar, Simona, Mrak, Valter, Bosnjak, Masa, Savarin, Monika, Sersa, Gregor, Cemazar, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157247/
https://www.ncbi.nlm.nih.gov/pubmed/32204304
http://dx.doi.org/10.3390/vaccines8010135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157247/
https://www.ncbi.nlm.nih.gov/pubmed/32204304
http://dx.doi.org/10.3390/vaccines8010135

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