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Intratumoral Gene Electrotransfer of Plasmid DNA Encoding shRNA against Melanoma Cell Adhesion Molecule Radiosensitizes Tumors by Antivascular Effects and Activation of an Immune Response
In this study, radiotherapy was combined with the gene electrotransfer (GET) of plasmid encoding shRNA against melanoma cell adhesion molecule (pMCAM) with dual action, which was a vascular-targeted effect mediated by the silencing of MCAM and an immunological effect mediated by the presence of plas...
Autores principales: | Kranjc Brezar, Simona, Mrak, Valter, Bosnjak, Masa, Savarin, Monika, Sersa, Gregor, Cemazar, Maja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157247/ https://www.ncbi.nlm.nih.gov/pubmed/32204304 http://dx.doi.org/10.3390/vaccines8010135 |
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