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Comparative Modeling of Drug Target Proteins

In this perspective, we begin by describing the comparative protein structure modeling technique and the accuracy of the corresponding models. We then discuss the significant role that comparative prediction plays in drug discovery. We focus on virtual ligand screening against comparative models and...

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Detalles Bibliográficos
Autores principales: Webb, B., Eswar, N., Fan, H., Khuri, N., Pieper, U., Dong, G.Q., Sali, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157477/
http://dx.doi.org/10.1016/B978-0-12-409547-2.11133-3