Neutralizing Monoclonal Antibodies against the Gn and the Gc of the Andes Virus Glycoprotein Spike Complex Protect from Virus Challenge in a Preclinical Hamster Model

Hantaviruses are the etiological agent of hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). The latter is associated with case fatality rates ranging from 30% to 50%. HCPS cases are rare, with approximately 300 recorded annually in the Americas. Recently, a...

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Detalles Bibliográficos
Autores principales: Duehr, James, McMahon, Meagan, Williamson, Brandi, Amanat, Fatima, Durbin, Alan, Hawman, David W., Noack, Danny, Uhl, Skyler, Tan, Gene S., Feldmann, Heinz, Krammer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157512/
https://www.ncbi.nlm.nih.gov/pubmed/32209676
http://dx.doi.org/10.1128/mBio.00028-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157512/
https://www.ncbi.nlm.nih.gov/pubmed/32209676
http://dx.doi.org/10.1128/mBio.00028-20

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