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Localized Hypermutation is the Major Driver of Meningococcal Genetic Variability during Persistent Asymptomatic Carriage

Host persistence of bacteria is facilitated by mutational and recombinatorial processes that counteract loss of genetic variation during transmission and selection from evolving host responses. Genetic variation was investigated during persistent asymptomatic carriage of Neisseria meningitidis. Inte...

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Detalles Bibliográficos
Autores principales: Green, Luke R., Al-Rubaiawi, Ali A., Al-Maeni, Mohammad A. R. M., Harrison, Odile B., Blades, Matthew, Oldfield, Neil J., Turner, David P. J., Maiden, Martin C. J., Bayliss, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157529/
https://www.ncbi.nlm.nih.gov/pubmed/32209693
http://dx.doi.org/10.1128/mBio.03068-19