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A MicroRNA Network Controls Legionella pneumophila Replication in Human Macrophages via LGALS8 and MX1

Legionella pneumophila is an important cause of pneumonia. It invades alveolar macrophages and manipulates the immune response by interfering with signaling pathways and gene transcription to support its own replication. MicroRNAs (miRNAs) are critical posttranscriptional regulators of gene expressi...

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Detalles Bibliográficos
Autores principales: Herkt, Christina E., Caffrey, Brian E., Surmann, Kristin, Blankenburg, Sascha, Gesell Salazar, Manuela, Jung, Anna L., Herbel, Stefanie M., Hoffmann, Kerstin, Schulte, Leon N., Chen, Wei, Sittka-Stark, Alexandra, Völker, Uwe, Vingron, Martin, Marsico, Annalisa, Bertrams, Wilhelm, Schmeck, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157531/
https://www.ncbi.nlm.nih.gov/pubmed/32209695
http://dx.doi.org/10.1128/mBio.03155-19