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MmpS5-MmpL5 Transporters Provide Mycobacterium smegmatis Resistance to imidazo[1,2-b][1,2,4,5]tetrazines

The emergence and spread of drug-resistant Mycobacterium tuberculosis strains (including MDR, XDR, and TDR) force scientists worldwide to search for new anti-tuberculosis drugs. We have previously reported a number of imidazo[1,2-b][1,2,4,5]tetrazines–putative inhibitors of mycobacterial eukaryotic-...

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Detalles Bibliográficos
Autores principales: Maslov, Dmitry A., Shur, Kirill V., Vatlin, Aleksey A., Danilenko, Valery N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157563/
https://www.ncbi.nlm.nih.gov/pubmed/32121069
http://dx.doi.org/10.3390/pathogens9030166