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c-Src controls stability of sprouting blood vessels in the developing retina independently of cell-cell adhesion through focal adhesion assembly

Endothelial cell adhesion is implicated in blood vessel sprout formation, yet how adhesion controls angiogenesis, and whether it occurs via rapid remodeling of adherens junctions or focal adhesion assembly, or both, remains poorly understood. Furthermore, how endothelial cell adhesion is controlled...

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Detalles Bibliográficos
Autores principales: Schimmel, Lilian, Fukuhara, Daisuke, Richards, Mark, Jin, Yi, Essebier, Patricia, Frampton, Emmanuelle, Hedlund, Marie, Dejana, Elisabetta, Claesson-Welsh, Lena, Gordon, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157583/
https://www.ncbi.nlm.nih.gov/pubmed/32108024
http://dx.doi.org/10.1242/dev.185405