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Vaccination Against Amyloidogenic Aggregates in Pancreatic Islets Prevents Development of Type 2 Diabetes Mellitus

Type 2 diabetes mellitus (T2DM) is a chronic progressive disease characterized by insulin resistance and insufficient insulin secretion to maintain normoglycemia. The majority of T2DM patients bear amyloid deposits mainly composed of islet amyloid polypeptide (IAPP) in their pancreatic islets. These...

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Detalles Bibliográficos
Autores principales: Roesti, Elisa S., Boyle, Christina N., Zeman, Daniel T., Sande-Melon, Marcos, Storni, Federico, Cabral-Miranda, Gustavo, Knuth, Alexander, Lutz, Thomas A., Vogel, Monique, Bachmann, Martin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157615/
https://www.ncbi.nlm.nih.gov/pubmed/32131431
http://dx.doi.org/10.3390/vaccines8010116