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Vaccination Against Amyloidogenic Aggregates in Pancreatic Islets Prevents Development of Type 2 Diabetes Mellitus
Type 2 diabetes mellitus (T2DM) is a chronic progressive disease characterized by insulin resistance and insufficient insulin secretion to maintain normoglycemia. The majority of T2DM patients bear amyloid deposits mainly composed of islet amyloid polypeptide (IAPP) in their pancreatic islets. These...
Autores principales: | Roesti, Elisa S., Boyle, Christina N., Zeman, Daniel T., Sande-Melon, Marcos, Storni, Federico, Cabral-Miranda, Gustavo, Knuth, Alexander, Lutz, Thomas A., Vogel, Monique, Bachmann, Martin F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157615/ https://www.ncbi.nlm.nih.gov/pubmed/32131431 http://dx.doi.org/10.3390/vaccines8010116 |
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