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Isoalantolactone Enhances the Antimicrobial Activity of Penicillin G against Staphylococcus aureus by Inactivating β-Lactamase during Protein Translation

β-Lactamase-positive Staphylococcus aureus is one of the most prevalent multidrug-resistant pathogens worldwide and is associated with increasing threats to clinical therapeutics and public health. Here, we showed that isoalantolactone (IAL), in combination with penicillin G, exhibited significant s...

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Detalles Bibliográficos
Autores principales: Zhou, Yonglin, Guo, Yan, Wen, Zhongmei, Ci, Xinxin, Xia, Lining, Wang, Yanling, Deng, Xuming, Wang, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157633/
https://www.ncbi.nlm.nih.gov/pubmed/32110983
http://dx.doi.org/10.3390/pathogens9030161