Influenza Hemagglutinin Nanoparticle Vaccine Elicits Broadly Neutralizing Antibodies against Structurally Distinct Domains of H3N2 HA

Influenza vaccine effectiveness varies annually due to the fast evolving seasonal influenza A(H3N2) strain and egg-derived mutations—both of which can cause a mismatch between the vaccine and circulating strains. To address these limitations, we have developed a hemagglutinin (HA)-based protein-dete...

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Detalles Bibliográficos
Autores principales: Portnoff, Alyse D., Patel, Nita, Massare, Michael J., Zhou, Haixia, Tian, Jing-Hui, Zhou, Bin, Shinde, Vivek, Glenn, Gregory M., Smith, Gale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157642/
https://www.ncbi.nlm.nih.gov/pubmed/32098409
http://dx.doi.org/10.3390/vaccines8010099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157642/
https://www.ncbi.nlm.nih.gov/pubmed/32098409
http://dx.doi.org/10.3390/vaccines8010099

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