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Recombinant Rabies Virus Overexpressing OX40-Ligand Enhances Humoral Immune Responses by Increasing T Follicular Helper Cells and Germinal Center B Cells

Rabies, caused by the rabies virus (RABV), remains a serious threat to public health in most countries. Development of a single-dose and efficacious rabies vaccine is the most important method to restrict rabies virus transmission. Costimulatory factor OX40-ligand (OX40L) plays a crucial role in the...

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Detalles Bibliográficos
Autores principales: Li, Yingying, Zhao, Ling, Sui, Baokui, Luo, Zhaochen, Zhang, Yachun, Wang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157680/
https://www.ncbi.nlm.nih.gov/pubmed/32210183
http://dx.doi.org/10.3390/vaccines8010144