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Subcutaneous Immunization of Leishmania HSP70-II Null Mutant Line Reduces the Severity of the Experimental Visceral Leishmaniasis in BALB/c Mice

Leishmania infantum parasites cause a severe form of visceral leishmaniasis in human and viscerocutaneous leishmaniasis in dogs. Recently, we reported that immunization with an attenuated L. infantum cell line, lacking the hsp70-II gene, protects against the development of murine cutaneous leishmani...

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Detalles Bibliográficos
Autores principales: Solana, José Carlos, Ramírez, Laura, Cook, Emma C. L., Hernández-García, Elena, Sacristán, Silvia, Martín, M. Elena, Manuel González, Víctor, Reguera, Rosa María, Balaña-Fouce, Rafael, Fresno, Manuel, Requena, José María, Iborra, Salvador, Soto, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157689/
https://www.ncbi.nlm.nih.gov/pubmed/32210040
http://dx.doi.org/10.3390/vaccines8010141