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Subcutaneous Immunization of Leishmania HSP70-II Null Mutant Line Reduces the Severity of the Experimental Visceral Leishmaniasis in BALB/c Mice
Leishmania infantum parasites cause a severe form of visceral leishmaniasis in human and viscerocutaneous leishmaniasis in dogs. Recently, we reported that immunization with an attenuated L. infantum cell line, lacking the hsp70-II gene, protects against the development of murine cutaneous leishmani...
Autores principales: | Solana, José Carlos, Ramírez, Laura, Cook, Emma C. L., Hernández-García, Elena, Sacristán, Silvia, Martín, M. Elena, Manuel González, Víctor, Reguera, Rosa María, Balaña-Fouce, Rafael, Fresno, Manuel, Requena, José María, Iborra, Salvador, Soto, Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157689/ https://www.ncbi.nlm.nih.gov/pubmed/32210040 http://dx.doi.org/10.3390/vaccines8010141 |
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