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The Utility of Human Immune System Mice for High-Containment Viral Hemorrhagic Fever Research

Human immune system (HIS) mice are a subset of humanized mice that are generated by xenoengraftment of human immune cells or tissues and/or their progenitors into immunodeficient mice. Viral hemorrhagic fevers (VHFs) cause severe disease in humans, typically with high case fatality rates. HIS mouse...

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Detalles Bibliográficos
Autores principales: Wozniak, David M., Lavender, Kerry J., Prescott, Joseph, Spengler, Jessica R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157695/
https://www.ncbi.nlm.nih.gov/pubmed/32098330
http://dx.doi.org/10.3390/vaccines8010098