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The Utility of Human Immune System Mice for High-Containment Viral Hemorrhagic Fever Research
Human immune system (HIS) mice are a subset of humanized mice that are generated by xenoengraftment of human immune cells or tissues and/or their progenitors into immunodeficient mice. Viral hemorrhagic fevers (VHFs) cause severe disease in humans, typically with high case fatality rates. HIS mouse...
Autores principales: | Wozniak, David M., Lavender, Kerry J., Prescott, Joseph, Spengler, Jessica R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157695/ https://www.ncbi.nlm.nih.gov/pubmed/32098330 http://dx.doi.org/10.3390/vaccines8010098 |
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