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Downregulation of A20 Expression Increases the Immune Response and Apoptosis and Reduces Virus Production in Cells Infected by the Human Respiratory Syncytial Virus

Human respiratory syncytial virus (HRSV) causes severe lower respiratory tract infections in infants, the elderly, and immunocompromised adults. Regulation of the immune response against HRSV is crucial to limiting virus replication and immunopathology. The A20/TNFAIP3 protein is a negative regulato...

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Detalles Bibliográficos
Autores principales: Martín-Vicente, María, González-Sanz, Rubén, Cuesta, Isabel, Monzón, Sara, Resino, Salvador, Martínez, Isidoro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157707/
https://www.ncbi.nlm.nih.gov/pubmed/32102364
http://dx.doi.org/10.3390/vaccines8010100