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Addition of Partial Envelope Domain II into Envelope Domain III of Dengue Virus Antigen Potentiates the Induction of Virus-Neutralizing Antibodies and Induces Protective Immunity

Dengue virus (DENV) comprises four serotypes in the family Flaviviridae and is a causative agent of dengue-related diseases, including dengue fever. Dengue fever is generally a self-limited febrile illness. However, secondary infection of patients with a suboptimal antibody (Ab) response provokes li...

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Detalles Bibliográficos
Autores principales: Park, Jisang, Lee, Hyun-Young, Khai, Ly Tuan, Thuy, Nguyen Thi Thu, Mai, Le Quynh, Jang, Yong-Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157711/
https://www.ncbi.nlm.nih.gov/pubmed/32075300
http://dx.doi.org/10.3390/vaccines8010088