Deletion of the Zinc Transporter Lipoprotein AdcAII Causes Hyperencapsulation of Streptococcus pneumoniae Associated with Distinct Alleles of the Type I Restriction-Modification System

The capsule is the dominant Streptococcus pneumoniae virulence factor, yet how variation in capsule thickness is regulated is poorly understood. Here, we describe an unexpected relationship between mutation of adcAII, which encodes a zinc uptake lipoprotein, and capsule thickness. Partial deletion o...

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Detalles Bibliográficos
Autores principales: Durmort, Claire, Ercoli, Giuseppe, Ramos-Sevillano, Elisa, Chimalapati, Suneeta, Haigh, Richard D., De Ste Croix, Megan, Gould, Katherine, Hinds, Jason, Guerardel, Yann, Vernet, Thierry, Oggioni, Marco, Brown, Jeremy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157770/
https://www.ncbi.nlm.nih.gov/pubmed/32234814
http://dx.doi.org/10.1128/mBio.00445-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157770/
https://www.ncbi.nlm.nih.gov/pubmed/32234814
http://dx.doi.org/10.1128/mBio.00445-20

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