Single-Dose, Intranasal Immunization with Recombinant Parainfluenza Virus 5 Expressing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike Protein Protects Mice from Fatal MERS-CoV Infection

Middle East respiratory syndrome coronavirus (MERS-CoV) can cause severe and fatal acute respiratory disease in humans and remains endemic in the Middle East since first being identified in 2012. There are currently no approved vaccines or therapies available for MERS-CoV. In this study, we evaluate...

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Detalles Bibliográficos
Autores principales: Li, Kun, Li, Zhuo, Wohlford-Lenane, Christine, Meyerholz, David K., Channappanavar, Rudragouda, An, Dong, Perlman, Stanley, McCray, Paul B., He, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157776/
https://www.ncbi.nlm.nih.gov/pubmed/32265331
http://dx.doi.org/10.1128/mBio.00554-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157776/
https://www.ncbi.nlm.nih.gov/pubmed/32265331
http://dx.doi.org/10.1128/mBio.00554-20

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