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A Chimeric Japanese Encephalitis Vaccine Protects against Lethal Yellow Fever Virus Infection without Inducing Neutralizing Antibodies

Recent outbreaks of yellow fever virus (YFV) in West Africa and Brazil resulted in rapid depletion of global vaccine emergency stockpiles and raised concerns about being unprepared against future YFV epidemics. Here we report that a live attenuated virus similar to the Japanese encephalitis virus (J...

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Detalles Bibliográficos
Autores principales: Mishra, Niraj, Boudewijns, Robbert, Schmid, Michael Alexander, Marques, Rafael Elias, Sharma, Sapna, Neyts, Johan, Dallmeier, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157777/
https://www.ncbi.nlm.nih.gov/pubmed/32265332
http://dx.doi.org/10.1128/mBio.02494-19