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Metabolism of Gluconeogenic Substrates by an Intracellular Fungal Pathogen Circumvents Nutritional Limitations within Macrophages

Microbial pathogens exploit host nutrients to proliferate and cause disease. Intracellular pathogens, particularly those exclusively living in the phagosome such as Histoplasma capsulatum, must adapt and acquire nutrients within the nutrient-limited phagosomal environment. In this study, we investig...

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Detalles Bibliográficos
Autores principales: Shen, Qian, Ray, Stephanie C., Evans, Heather M., Deepe, George S., Rappleye, Chad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157778/
https://www.ncbi.nlm.nih.gov/pubmed/32265333
http://dx.doi.org/10.1128/mBio.02712-19