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Epistatic Interplay between Type IV Secretion Effectors Engages the Small GTPase Rab2 in the Brucella Intracellular Cycle

Intracellular bacterial pathogens remodel cellular functions during their infectious cycle via the coordinated actions of effector molecules delivered through dedicated secretion systems. While the function of many individual effectors is known, how they interact to promote pathogenesis is rarely un...

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Detalles Bibliográficos
Autores principales: Smith, Erin P., Cotto-Rosario, Alexis, Borghesan, Elizabeth, Held, Kiara, Miller, Cheryl N., Celli, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157780/
https://www.ncbi.nlm.nih.gov/pubmed/32234817
http://dx.doi.org/10.1128/mBio.03350-19