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YejM Modulates Activity of the YciM/FtsH Protease Complex To Prevent Lethal Accumulation of Lipopolysaccharide

Lipopolysaccharide (LPS) is an essential glycolipid present in the outer membrane (OM) of many Gram-negative bacteria. Balanced biosynthesis of LPS is critical for cell viability; too little LPS weakens the OM, while too much LPS is lethal. In Escherichia coli, this balance is maintained by the YciM...

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Detalles Bibliográficos
Autores principales: Guest, Randi L., Samé Guerra, Daniel, Wissler, Maria, Grimm, Jacqueline, Silhavy, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157816/
https://www.ncbi.nlm.nih.gov/pubmed/32291302
http://dx.doi.org/10.1128/mBio.00598-20