Intercellular Transmission of a Synthetic Bacterial Cytotoxic Prion-Like Protein in Mammalian Cells

RepA is a bacterial protein that builds intracellular amyloid oligomers acting as inhibitory complexes of plasmid DNA replication. When carrying a mutation enhancing its amyloidogenesis (A31V), the N-terminal domain (WH1) generates cytosolic amyloid particles that are inheritable within a bacterial...

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Detalles Bibliográficos
Autores principales: Revilla-García, Aida, Fernández, Cristina, Moreno-del Álamo, María, de los Ríos, Vivian, Vorberg, Ina M., Giraldo, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157824/
https://www.ncbi.nlm.nih.gov/pubmed/32291306
http://dx.doi.org/10.1128/mBio.02937-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157824/
https://www.ncbi.nlm.nih.gov/pubmed/32291306
http://dx.doi.org/10.1128/mBio.02937-19

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