ADAMTS-1 and syndecan-4 intersect in the regulation of cell migration and angiogenesis

ADAMTS-1 is an extracellular protease with critical roles in organogenesis and angiogenesis. Here we demonstrate a functional convergence of ADAMTS-1 and the transmembrane heparan sulfate proteoglycan syndecan-4 in influencing adhesion, migration and angiogenesis. Knockdown of ADAMTS-1 in endothelia...

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Detalles Bibliográficos
Autores principales: Lambert, Jordi, Makin, Kate, Akbareian, Sophia, Johnson, Robert, Alghamdi, Abdullah A. A., Robinson, Stephen D., Edwards, Dylan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157938/
https://www.ncbi.nlm.nih.gov/pubmed/32269093
http://dx.doi.org/10.1242/jcs.235762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157938/
https://www.ncbi.nlm.nih.gov/pubmed/32269093
http://dx.doi.org/10.1242/jcs.235762

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