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Multiple links between 5-methylcytosine content of mRNA and translation

BACKGROUND: 5-Methylcytosine (m(5)C) is a prevalent base modification in tRNA and rRNA but it also occurs more broadly in the transcriptome, including in mRNA, where it serves incompletely understood molecular functions. In pursuit of potential links of m(5)C with mRNA translation, we performed poly...

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Detalles Bibliográficos
Autores principales: Schumann, Ulrike, Zhang, He-Na, Sibbritt, Tennille, Pan, Anyu, Horvath, Attila, Gross, Simon, Clark, Susan J., Yang, Li, Preiss, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158060/
https://www.ncbi.nlm.nih.gov/pubmed/32293435
http://dx.doi.org/10.1186/s12915-020-00769-5