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Baseline levels of dynamic CD4(+) T cell adhesion to MAdCAM-1 correlate with clinical response to vedolizumab treatment in ulcerative colitis: a cohort study

BACKGROUND: While the number of therapeutic options for treating inflammatory bowel diseases (IBD) is increasing, evidence for rational treatment decisions is scarce in many cases. In particular, appropriate biomarkers to predict the response to the anti-α4β7 integrin antibody vedolizumab are curren...

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Detalles Bibliográficos
Autores principales: Allner, Clarissa, Melde, Michaela, Becker, Emily, Fuchs, Friederike, Mühl, Laura, Klenske, Entcho, Müller, Lisa, Morgenstern, Nadine, Fietkau, Konstantin, Hirschmann, Simon, Atreya, Raja, Atreya, Imke, Neurath, Markus F., Zundler, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158080/
https://www.ncbi.nlm.nih.gov/pubmed/32293299
http://dx.doi.org/10.1186/s12876-020-01253-8