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Maternal high-fat diet induces sex-specific changes to glucocorticoid and inflammatory signaling in response to corticosterone and lipopolysaccharide challenge in adult rat offspring

BACKGROUND: Maternal obesity as a result of high levels of saturated fat (HFD) consumption leads to significant negative health outcomes in both mother and exposed offspring. Offspring exposed to maternal HFD show sex-specific alterations in metabolic, behavioral, and endocrine function, as well as...

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Detalles Bibliográficos
Autores principales: Wijenayake, Sanoji, Rahman, Mouly F., Lum, Christine M. W., De Vega, Wilfred C., Sasaki, Aya, McGowan, Patrick O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158103/
https://www.ncbi.nlm.nih.gov/pubmed/32293490
http://dx.doi.org/10.1186/s12974-020-01798-1