HSP90 inhibitor 17AAG attenuates sevoflurane-induced neurotoxicity in rats and human neuroglioma cells via induction of HSP70

BACKGROUND: 17AAG has been extensively studied for its antitumor effects that protect cells from lethal stress by maintaining protein stability. The role of 17AAG in sevoflurane-induced neuronal injury has never been studied. We aim to investigate the effect of 17AAG on sevoflurane-induced neurotoxi...

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Detalles Bibliográficos
Autores principales: Liu, Min, Li, Moyun, Zhou, Yu, Zhou, Qian, Jiang, Yugang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158111/
https://www.ncbi.nlm.nih.gov/pubmed/32293462
http://dx.doi.org/10.1186/s12967-020-02332-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158111/
https://www.ncbi.nlm.nih.gov/pubmed/32293462
http://dx.doi.org/10.1186/s12967-020-02332-w

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