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Abnormal mitosis in reactive astrocytes

Although abnormal mitosis with disarranged metaphase chromosomes or many micronuclei in astrocytes (named “Alzheimer I type astrocytes” and later “Creutzfeldt-Peters cells”) have been known for nearly 100 years, the origin and mechanisms of this pathology remain elusive. In experimental brain insult...

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Detalles Bibliográficos
Autores principales: Sosunov, Alexander, Wu, Xiaoping, McGovern, Robert, Mikell, Charles, McKhann, Guy M., Goldman, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158149/
https://www.ncbi.nlm.nih.gov/pubmed/32293551
http://dx.doi.org/10.1186/s40478-020-00919-4